This study evaluated the effects of foliar application of ordinary and nano-particles of zinc and iron oxide on the responses tolerant and sensitive wheat (kavir and Tajan) and corn (seed mass and Sc 704) genotypes to three levels (0, 75 and 150 mmol kCal) of salinity. Two pot experiments were conducted to study wheat and corn plants separately. Each experiment was arranged as factorial in a randomized complete block design with four replications. Spray treatments were included iron oxide, zinc oxide, nano-sized iron oxide, nano-sized zinc oxide, a mixture of nano-sized of iron and zinc oxide and a no-spray treatment as control. In both crops wheat and corn plant height, leaf area, shoot and root dry matter, chlorophyll content, photosynthesis rate, stomatal conductivity, photochemical efficiency, the concentration of K, Fe and Zn was decreased, while the enzyme activity of catalase (CAT), peroxidase (POX), ascorbat peroxidase (APX), glotation reductase (GR), superoxide dismutase (SOD), and the concentration of MDA, proline, soluble carbohydrate and Na was increased under saline conditions. Foliar application of ordinary and nano-sized zinc and iron oxides had significant positive effects on plant height, leaf area, shoot and root dry matter, chla/ chlb ratio, photochemical efficiency and the concentration of Fe and Zn of in both crops, and also on the activity of CAT and SOD in wheat and on the activity of CAT in corn. The extent of the positive effects of iron oxide in wheat on plant height, photochemical efficiency and Fe concentration was significantly larger with application of nano compared to ordinary form of iron oxide. There were no significant effects of foliar application of zinc and iron oxide on the concentration of proline, soluble carbohydrate and MDA in both crops and on the activity of APX, POX and GR in wheat and on the activity of SOD, APX, POX and GR in corn. The interactions of salinity and genotype were significant in wheat on plant height, leaf area, shoot and root dry matter, chlorophyll content, the concentration of MDA, proline, soluble carbohydrate, the enzyme activity of all tested antioxidant enzymes and on K concentration and the K/Na ratio and in corn it was significant for all abovementioned traits except for chlorophyll and MDA content and GR activity. Genotypes kavir (wheat) and seed mass (corn) were recognized tolerant as compared to Tajan and Sc 704. The increase in the concentration of K, proline, soluble carbohydrate, SOD activity and K/Na ratio under saline condition was more pronounced in tolerant than in sensitive genotypes. The results from this experiment show that the application of nano particles of iron and zinc oxide can have positive effects on some growth characteristics of wheat and corn, however, under conditions of this experiment, it seems that the application of nano particles of these compounds may not be superior compare to ordinary forms in alleviating negative effect of salinity. Key words : Sunflower, salinity, foliar application, iron sulpate, zinc oxide, nano-particles, anti oxidant enzymes.