owadays, the usage of sensors in order to determination of trace amounts of biological species and drugs compounds with highly selective has attracted enormous interest. In this thesis, in order to improve the efficiency and sensitivity of electrochemical sensors, various nanomaterials have been used to modify the detector electrodes. Finally, a simple and new electrochemical sensor was made to selectively determination the insecticide trace amounts of Indoxacarb. The process made of this sensor was modification the surface of glass carbon electrode with an imprinted polymer by sol-gel method on the surface of multi-walled carbon nanotubes, quantum dots, and graphitic carbon nitride. The study of sensor construct and its function was performed by using cyclic voltammetry and differential pulse voltammetry methods. Also, electrochemical impedance spectroscopy was used in order to confirm the fabrication steps of the modified electrode and to improve the obtained results. The detection of the interaction between the molecular imprinted polymer and the dominant molecule (Indoxacarb) was followed by measuring the oxidation-reduction current changes of the potassium hexacyano ferrate solution as a tracer at the glass carbon electrode surface. Under optimum conditions, the current response for Indoxacarb was obtained in the linear range of 0.20 µM–10.0 nM and a detection limit of 7.1 nM. This sensor has been successfully used for the determination of Indoxacarb in samples of Zayandehrood river water. The results showed that the designed sensor has possessed advantages such as sensitivity, selectivity and simplicity.