Rice, as one of the most important crop grain in the world, is a staple food for more than two billion people in the world and its cultivation area and production is in third place among the crops in the world. Because of arid and semi-arid climate conditions, high phosphorous fixation in the soil, using the bicarbonate irrigation water, and low amount of organic matter in the soil; micronutrients deficiency such as iron often appears under such conditions. One of the strategies for this challenge in the soil is to select tolerant genotypes to iron deficiency (iron-use-efficiency genotypes) or use cultivars with high micronutrient uptake abilities. Salinity is also considered to be as one of the most important abiotic stress and reduces growth, quality, and yield of crops. One of the suitable strategies for cultivating plants under salinity condition is to select salinity-tolerant genotypes. Therefore, this research was conducted to evaluate Iranian rice genotypes under enrichment of chelated iron fertilizer in two levels (normal and iron deficient) and investigate tolerant and sensitive genotype responses to enhanced salinity levels. The experiments were separately carried out in the green house of Agricultural College, Isfahan University of Technology in 2013 and 2014. In the first experiment, twelve Iranian rice genotypes (in three groups of north landrace, north improved, and Iranian central cultivars) were evaluated in two levels of chelated iron fertilizer (5 and 50 mM in Yushida nutrient solution). In the second experiment, four genotypes with different sensitivity to iron deficiency (Zayandé-Roud, Kouhrang, Sazandegi, and Jozdan) were compared under four levels of salinity (0, 30, 60, 90 mM of chloride sodium). Both experiments were carried out in the form of factorial based on a completely randomized design with four replicates. The results of first experiment showed that iron content, shoot, root and total dry weights, leaf area, the length and volume of plant roots, and the number of tiller were significantly affected by genotypes, iron fertilizer, and their interaction. The average of individual total dry weight was about 0.215, 0.138, and 0.255 g in north landraces, north improved, and Iranian central cultivars under normal treatment of iron condition, respectively. However, 25.7, 35.2, and 23.0% reductions were noted under iron deficiency, respectively. Dependent on the reduced amount of biomass under iron deficiency condition; among central, north landraces, and north improved cultivars, the least and most sensitivity to iron deficiency in nutrient solution were Zayandé-Roud, Musa-Tarom, and Bejar; Jozdan, Amol 2, and Shiroudi; respectively. In the second experiment, dry weight, potassium and calcium contents in shoot and root, total dry weight, plant height, stay-green index, leaf area, the number of tiller; raceme weight, length, number and weight of kernel in plant were significantly affected by genotype, salinity, and their interaction. All of the measured traits reduced as salinity level increased. Also electrolyte leakage, sodium concentration, the Na/K and Na/Ca ratios in the shoot and root were significantly affected by genotype, salinity, and their interaction. However, these traits increased as salinity level increased. Decrease or increase was observed in the length of root depending on genotypes and salinity levels. Although interaction between genotype and salinity in root volume wasn’t significant, increased level of salinity caused a decrease in root volume. In the second experiment, the reduced amount of biomass under salinity stress was more than first experiment under iron deficiency treatment condition. Through increased in the level of salinity in the nutrient solution caused reduction in the individual biomass in all four genotypes, the least and most decreases were appeared in Zayandé-Roud and jozdan, respectively. In both experiments, Zayandé-Roud and Jozdan were the most tolerant and sensitive cultivars, respectively, under iron deficiency and salinity stress. The results of these experiments showed a considerable genetic variation in the measured traits of twelve Iranian landraces and improved cultivars under two levels of (5 and 50mM) iron chelated conditions as well as four genotypes under sodium chloride salinity stress in the nutrient solution. Based on the reduced amount of individual biomass under iron deficiency, Zayande-roud and Kouhrang were tolerant in contrast to Sazandegi and Jozdan that were sensetive. Also based on Na/K ratio, Kouhrang and Jozdan were more sensitive than Zayande-roud and Sazandegi in response to salinity. Keywords : Rice genotypes, Chelated Iron Fertilizer, Iron Deficiency, Salinity, Sodium, Potassium, Calcium, Electrolyte leakage.