Nowadays limited fresh water resources available in the world has polluted by various types of contaminants including domestic sewage, industrial and agricultural drainage water. Unconventional water resources include industrial wastewater, saltwater, brackish and saline drainage water of agricultural. There are different methods of unconventional water treatment. Methods of treatment unconventional water are often not cost effective and is economically feasible only for drinking water. Biodegradation and phytoremediation are two efficient and cheap methods for desalination water. The aim of this study was to investigate the behavior of Vetiver Grass, at different salinities and reduction some of chemical parameter in salt water for application in agriculture or discharge into surface and ground water resources. This study was conducted as multi-factorial in a completely randomized design including three levels of salinity (1, 10 and 14 dS/m) and two planting densities (10 plants and 20 plants Vetiver). Different chemical parameter were measured including EC, pH, calcium, magnesium, sodium and nutrients NPK and detention times of 3, 7 and 14 days were considered. The results showed that Vetiver plants grow well up to salinity 14 dS/m. The result show that there is no significant difference between 10 and 20 plants. Vetiver plant is able to decrease the drainage water EC within 14 days by 15% and ions of sodium, calcium, magnesium, nitrate, phosphate and potassium by 15%, 35%, 25%, 26%, 40% and 20 %. Keywords: Desalination, drainage water, phytoremediation, Vetiver grass.