Because of shortage of water, the use of wastewater for irrigation is becoming more important. Wastewater contains fertilizers and if manage properly wastewater can increase soil fertility. Soil nitrogen losses due to low fertilizer application efficiency, causes environmental pollution by polluting groundwater and surface water with nitrate and ammonium. Nitrogen losses especially in irrigated lands and in coarse textured soils cause significantly high nitrogen concentrations in surface and groundwater. So, using natural and non-toxic materials that increase fertilizer application efficiency and decrease nitrate leaching is quite important. Zeolites are natural, non-toxic and inexpensive materials that because of high cation exchange capacity and because of releasing plant nutrient, considered to be a good soil amendment for plant growth. The aims of this study were to investigate the influence of size (mm and ?m) and usage (20 and 60 grams per kilogram of soil) of natural zeolite of clinoptilolite (CP) and surfactant-modified zeolite (SMZ) on soil nitrate and ammonium leaching and on wheat plant performance using soil columns and applying wastewater for irrigation. The experimental soils were placed in PVC columns with 9 cm inner diameter and 65 cm height. The experiment was factorial with completely randomized design with three replications for each treatment. The total amount of released NO 3 -N from modified columns by SMZ and CP were 32 and 21 percent lower as compared to the control treatment. These amendments simultaneously improved wheat plant growth and increased the amount of nitrogen uptake by plants. The amount of nitrogen that was taken by plant for CP treatment as compared to the SMZ treatment was significantly higher (at probability level of 5%). Results showed that CP and SMZ amendments are eco-friendly materials and are effective to control soil nitrate leaching and to improve the efficiency of nitrogen uptake by plants. Keywords: Natural zeolite, Surfactant-modified zeolite, Wheat, Wastewater, Soil column, Nitrate leaching