In the current era by increasing competition and all the changes and developments in nowadays technologies, the innovation and improved performance of organization’s products and services are necessary in order for them to deal with uncertainty, maintain their position, expand competition and utilizing appropriate resources. Total quality management is a strategy, which is capable of using tools to improve learning, and create competitive advantages for organizations. Organizational learning causes the development, earn, transfer and implementation of a new knowledge, which will lead to performance improvement and satisfaction. TQM has attracted a lot of attention by industries and academic sciences in the past two decades. TQM is one of the most famous, sturdy concepts and developed and modern philosophy and management system at the end of last century, which had fascinating and deep effects. These days, the gap between nations and societies is the border between knowledge and ignorance, therefore the main challenge is knowing and capable human resource. The most important and the most valuable resources of all organizations are human resources; therefore, the human resources have an essential role in the growth, dynamism and improvement or the cause of the failure of their organizations. Therefore, it can be said that without efficient human resources, achieving organization’s goals, optimization and progress is impossible.Enhancing the performance, efficiency and effectiveness or productivity of employees without their participation, willingness and motivation cannot be achieved, so organization’s managers and institutions use different ways in order to create work motivation their employees which TQM includes issues of quality, satisfaction and efficiency improvement. In this study, the effect of TQM on satisfaction and performance of non-academic staff committee employees of Isfahan University of Technology has been considered. The data was collected using questionnaire from statistical population consisted of 240 non-academic staff of Isfahan university of technology and then the data analysis was done using statistical methods (descriptive and inferential statistics) by software. The results showed that there is a significant positive relationship between job satisfaction and the components of manager’s commitment and effective leadership, human resource management, employee involvement, employee empowerment, communication and teamwork, continuous improvement, reward and punishment system. Also between employee performance and manager’s commitment components and effective leading, human resource management, employee involvement, communication and teamwork, organizational commitment, continuous improvement, reward and punishment system, there is a significant positive relationship. according to the results it was found that, there is a significant positive relationship between the two dependent variables satisfaction and employee performance.