This study was conducted to investigate agronomic traits and the relationship between yield and its components in some breeding lines of safflower. In this experiment, 20 genotypes of safflower were evaluated for different agronomic traits in a randomized complete block design with three replications in 2009, at the Research Farm of Isfahan University of Technology located, in Falavarjan. The results of analysis of variance showed that the genotypes were significantly different for all of the studied traits, except for days to emergence. In this experiment, seed yield of the genotypes varied from 2095 to 3351 Kg/ha, and the lowest and highest means of seed yield was belong to A2 and C4110 genotypes, respectively. The seed yield for the local population of Kuseh (as the check variety) was 2628 Kg/ha, and 7 genotypes had significantly more seed yield than this populatiopn. Also, Kuseh population had the most means of days to maturity and plant height among the genotypes. Seed oil content of the genotypes significantly differed and ranged from 26/03% for C4110 to 33/23% in S149 genotype. Genetic and phenotypic correlation coefficients showed that number of capitula/plant, number of seed/capitulum were the most important seed yield components and they had the highest positive correlation with seed yield; however, seed weight showed a negative genetic and phenotypic correlation with seed yield. Based on the regression analysis, number of capitula/plant contributed in 66% of seed yield variation; but, this variable along with capitulum diameter contributed in 74% of the variation for seed yield. Path analysis showed that capitula/plant had the most direct positive effect on seed yield with no significant indirect effect through the other traits. Also, number of seeds/capitulum had a high direct and positive effect and also considerable indirect effect via number of capitula/plant on seed yield. key word: safflower, agrojomic traits, Genetic diversity, correlation