One of the powerful experimental approaches in the field of neuroscience to understanding spatiotemporal neural network is Optogenetics; Optogenetics is considered as a combination of genetic and opticalmethods, to optical control cells with light by expressing light-sensitive ion channels in neurons. Neural representation, computation, the shaping of communication among cortical neurons, even neurological and neuropsychiatric disorders can be explained by spatiotemporal gamma oscillations in neo-cortex. In this project we demonstrated the constant Optogenetics stimulation based on the ChR2 opsin under the control of the CaMK ll ? promotor which can induce sustained narrowband gamma oscillations in nonhuman visual cortex experimentally. We examine and analyze the effect of induced gamma oscillations on visual processing and report the direct observation of gamma oscillations as spatiotemporal waves induced by targeted Optogenetics stimulation, recorded by intra-cortical one-channel extracellular techniques in Rats during their comatose states. We will trying to find and improving one of the models that governs on experimental results, we focus on Wilson –Cowan model which is used for some different study in the area of Optogenetics.