Several studies have been carried out to remove and reduce p-nitrophenol from contaminated water and industrial effluents, and various methods have been used such as catalytic oxidation, Electro-Fenton, electrochemical, microbial degradation, and so on. But these methods have problems such as low sensitivity, high cost, the need for specific temperature conditions and a long time. One of the ways in which scientists have considered the catalytic hydrogenation of these materials in recent years is to convert them into aminophenol derivatives. Therefore, the thesis attempts to reduce the aminophenol derivative by making heterogeneous nanocatalyst, toxic substances and carcinogens of p-nitrophenol. For this purpose, silver and palladium nanoparticles were placed on a zinc oxide and the catalyst was identified with techniques such as BET, FESEM, EDX mapping, XRD, TEM, XPS, and ICP. And then, after selecting the best nanocatalysts, to evaluate for the reduction of p-nitrophenol to p-aminophenol in the presence of NaBH 4 as a reducing agent and at ambient temperature and pressure, and factors affecting the reaction, including the amount of reducing agent, the catalyst type and the percentage of the metal present They were examined. The reaction was followed by UV-Vis spectroscopy and the results were that the catalyst Ag (8.9 wt%)-Pd (0.6 wt%) /ZnO was considered as the optimal catalyst using this catalyst, the reaction finished in 3 min with k=0.76 min -1 The results reported so far in various sources have often been used a lot of the amount of reducing agent or catalyst, or the reaction has been completed over a longer period of time. In addition to using the minimum amount of catalyst and NaBH 4 , the completion time of the reaction is also appropriate.