Nowadays, most of the researches are focused on metal nano particles. They have unique properties on magnetic, electronic, optical and chemical behavior compared to bulk materials, because of their large surface area to volume ratio. Transition metal nano particles have the high catalytic activities in organic reactions. But the soluble metal nano particles have some problems such as recycling and separation of these catalysts from reactions. To solve these problems it would be better to immobilize them on suitable support materials and use them as heterogeneous catalysts. Therefore, most of current researches are focused on modification of different supports for immobilization of metal nano particles. However, inorganic solids such as silica, carbon, clay, zeolites and mixed oxides are widely used to carry metal nano particles. In the first project, nano-hybridized Ni-Mo was prepared in reverse micelle of bis-(2-ethylhexyl) sulfosuccinate (AOT) then was deposited on the surface of mixed oxide such as Al 2 O 3 /TiO 2 and Al 2 O 3 /ZrO 2 . These mixed oxides are synthesized by sol- gel procedure. Depositing of these nano particles on the surface was done by using ultrasonic waves. For characterization of these catalysts, XRD, Uv-vis, BET, TEM analysis were used. Then these catalysts were used in oxidation of toluene. The products were analyzed by GC and GC-MS. Furthermore, the reaction conditions were changed for the reaction. In the second project, an organo-bentonite was loaded with the first generation of amidoamine hyperbranch cascade, 3, 3’-(dodecylazanediyl) bis(N-(2-(2-aminoethylamino)ethyl)propionamide (DAEP), which has a long aliphatic tail (C 12 ) and a hydrophilic head. The hydrophilic head of DAEP has served as a pincer-type chelating agent for Pd nano-particles. A similar chelating agent was immobilized onto the surface of a porous silica gel. The modified bentonite and the modified silica gel were used as a support with chelating sites for immobilization of the palladium nano-particles. The catalytic performance was examined in the Heck reaction. The products were analyzed by GC and GC-MS. Furthermore, the reaction conditions were optimized for the reaction. The catalysts showed excellent activity towards Heck coupling. For this reaction, Iodobenzene was reacted with some olefins such as methyl acrylate, styrene, tert-butyl acrylate, acrylic acid, methyl vinyl ketone. DMF and NaOAc were used as solvent and base respectively. The reaction was done in 130 ? C. The best reaction time for modified bentonite catalyst was 12 h and the best reaction time for modified silica catalyst was 29 h. The immobilized palladium complexes efficiently catalyzed the Heck reaction, are recyclable under aerobic conditions and exhibit hardly any leaching.